American Airlines, flight 11, flew into the North Tower of the World Trade Center on September 11, 2001 and marked the first commercial flight in the United States used in an act of terrorism that killed everyone on board.
The synopsis in brief:
American Airlines Flight 11 from Boston to Los Angeles - lives lost -81 passengers, 9 flight attendants, 2 pilots.
Timeline:
Scheduled 745am departure from Boston Logan Airport - leaves a few minutes late.
9/11 ringleader Mohamed Atta is on board, and would ultimately pilot the plane into the North Tower of the World Trade Center.
8:46am AA11 flies into the North Tower between the 93-99 floors, killing all on board and hundreds immediately in the Tower.

